Gamma interferon-based immunodiagnosis of tuberculosis: comparison between whole-blood and enzyme-linked immunospot methods.

نویسندگان

  • Elisabeth Schölvinck
  • Katalin A Wilkinson
  • Adam O Whelan
  • Adrian R Martineau
  • Michael Levin
  • Robert J Wilkinson
چکیده

The gamma interferon secretion levels of 52 adults whose T cells had been stimulated with the Mycobacterium tuberculosis antigens CFP-10 and ESAT-6 were measured by enzyme-linked immunospot methods and a whole-blood-based assay. The test results correlated well (r = 0.689, P < 0.0001). Its simple format and use of only small volumes of blood make the whole-blood assay suitable for pediatric practice and field trials.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 42 2  شماره 

صفحات  -

تاریخ انتشار 2004